Prisma Health

Prisma Health is a not-for-profit health organization based in South Carolina, dedicated to providing comprehensive healthcare services to over 1.4 million patients annually.

Formed in November 2017 through the merger of Palmetto Health and the Greenville Health System, Prisma Health has become the largest private, non-profit healthcare system in the state.

Service Regions

The organization operates across two primary regions: the Midlands and the Upstate.

In the Midlands, Prisma Health serves the Columbia area and surrounding communities, while in the Upstate, it covers the Greenville area and its environs.

Notably, 51% of South Carolinians reside within Prisma Health's 21-county service area, underscoring its significant impact on the state's healthcare landscape.

Network and Facilities

The extensive network includes 12 acute care and specialty hospitals, such as Prisma Health Richland Hospital in Columbia and Prisma Health Greenville Memorial Hospital in Greenville.

These facilities offer a wide range of services, including:

• Behavioral care
• Cancer treatment
• Heart care
• Obstetrics
• Orthopedics
• Neonatology
• Stroke care
• Trauma services

The organization also operates specialty hospitals like Prisma Health Children's Hospital and Prisma Health Heart Hospital, catering to specific patient needs.

Expansion

In December 2024, Prisma Health expanded its reach beyond South Carolina by merging with Blount Memorial Hospital in Maryville, Tennessee.

This merger marked the first time Prisma Health extended its services outside of South Carolina, reflecting its commitment to improving health outcomes in neighboring regions.

Headquarters

The organization's headquarters are located on the property of Greenville Memorial Hospital in Greenville, South Carolina.

This central location facilitates close alignment between administrative functions and clinical operations, supporting Prisma Health's mission to deliver high-quality, compassionate care to the communities it serves.

Locations

• Columbia, SC, USA – Serving the Midlands area

Prisma Health's dedication to excellence is evident in its comprehensive services, extensive network of facilities, and ongoing efforts to enhance healthcare access and quality across South Carolina and beyond.