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Hydrocodone is a prescription opioid used to manage moderate to severe pain when other treatments are inadequate. It must be prescribed by a licensed healthcare provider following a clinical assessment and used exactly as directed. For immediate-release hydrocodone, typical adult dosing is 5–10 mg every 4–6 hours as needed for pain. Many products are combined with acetaminophen, so total daily acetaminophen should not exceed 4,000 mg from all sources. Avoid alcohol and other sedatives, use the lowest effective dose, and follow close medical supervision.