Supervisor, GMP Facilities

Lexington, MA, USA|Onsite

Job Overview

Employment Type

Full-time

Compensation

Salary

Range $107,300.00 - $132,500.00

Work Schedule

Standard Hours

Benefits

Generous vacation time

Public holidays observed

Volunteer days

Long term incentive plans

employee stock purchase plans

Employee wellbeing benefits

Fitness Reimbursement

Tuition sponsoring

Professional development plans

Job Description

Ultragenyx Pharmaceutical Inc. is a pioneering biopharmaceutical company dedicated to developing novel therapies for rare and ultra-rare diseases. Founded with a mission to transform the lives of patients suffering from rare genetic disorders, Ultragenyx has established itself as an innovative leader in the rare disease medicine sector. The company operates with a patient-centric approach, striving to bring impactful and life-changing treatments to patients and caregivers who often face limited options. With a commitment to scientific excellence, rapid development, and fair pricing, Ultragenyx aims to create a collaborative ecosystem that supports the development and delivery of cutting-edge therapies for rare diseases worldwide.

Ultragenyx fosters a culture of inclusivity, continuous learning, and growth, emphasizing the well-being and professional development of its employees. The company values a supportive and enriching workplace where individuals can thrive both personally and professionally. The organization is committed to maintaining an environment that people would be proud to share with their family and friends, underlining its dedication not only to patients but also to its workforce.

The Facilities Supervisor role at Ultragenyx is a critical position focused on ensuring that all manufacturing and laboratory facilities and equipment are maintained efficiently and compliantly within a regulated Good Manufacturing Practice (GMP) environment. This full-time, on-site role involves supervising maintenance technicians and contractors to support the seamless operation of GMP-critical equipment and systems. This position requires creating and managing preventive and corrective maintenance schedules that minimize downtime and meet stringent regulatory standards.

The Facilities Supervisor will also oversee accurate documentation through Computerized Maintenance Management Systems (CMMS) and lead troubleshooting efforts with root cause analysis to resolve equipment failures. Collaboration with cross-functional teams in Quality Assurance, Manufacturing, and Engineering is key to ensuring readiness for audits, production, and compliance standards. The role demands experience with GMP requirements, regulatory agencies such as FDA and EMA, and familiarity with HVAC, clean utilities, and critical equipment.

Ultragenyx provides a dynamic and challenging work environment where the Facilities Supervisor can contribute meaningfully to advancing rare disease medicine. This role offers the opportunity to engage in leadership, mentoring, and technical problem-solving while participating in continuous improvement of maintenance programs and compliance initiatives. Candidates can expect to work in a fast-paced environment that balances operational efficiency with quality and regulatory adherence. This position exemplifies Ultragenyx’s commitment to excellence in patient care by maintaining the infrastructure that supports the development and manufacturing of transformative therapies.

Job Requirements

Associate or bachelor’s degree in engineering, Facilities Management, or a related field (or equivalent combination of education and experience)
6+ years of maintenance experience in a GMP-regulated pharmaceutical, biotechnology, or medical device environment
2+ years of supervisory or team lead experience in a maintenance or facilities role
Strong knowledge of GMP, FDA, EMA, and other applicable regulatory requirements and industry standards
Proficiency with CMMS (e.g. Blue Mountain, Infor EAM, Maximo) and Microsoft Office applications (Excel, Word, Outlook, PowerPoint)
Excellent communication, leadership, and problem-solving skills with the ability to manage cross functional collaboration
Demonstrated experience in planning, scheduling, and executing preventive and corrective maintenance programs
Familiarity with HVAC, clean utilities (e.g., WFI, clean steam, compressed air), and critical manufacturing equipment
Experience supporting deviation investigations, root cause analysis, and CAPA implementation
Ability to read and interpret technical drawings, equipment manuals, and engineering specifications
Strong organizational skills and attention to detail in a fast-paced, compliance-driven environment
Stand for extended periods of time with periodic stooping / bending / kneeling
Ability to climb ladders and stairs of various heights
Able to lift, push, pull up to 50lbs
Work in a controlled environment requiring GxP gowning and wear protective clothing over the head, face, hands, feet, and body
This requires the ability to change clothes into appropriate gowning and personal protective equipment
Certain tasks may require use of a respirator
medical clearance will be required in advance
Must remove all make-up, jewelry, and contact lenses while in the manufacturing environment
Working in temperature-controlled environments (cold rooms)

Job Qualifications

Associate or bachelor’s degree in engineering, Facilities Management, or a related field
6+ years of maintenance experience in a GMP-regulated pharmaceutical, biotechnology, or medical device environment
2+ years of supervisory or team lead experience in a maintenance or facilities role
Strong knowledge of GMP, FDA, EMA, and other applicable regulatory requirements and industry standards
Proficiency with CMMS (e.g. Blue Mountain, Infor EAM, Maximo) and Microsoft Office applications (Excel, Word, Outlook, PowerPoint)
Excellent communication, leadership, and problem-solving skills with the ability to manage cross functional collaboration
Demonstrated experience in planning, scheduling, and executing preventive and corrective maintenance programs
Familiarity with HVAC, clean utilities (e.g., WFI, clean steam, compressed air), and critical manufacturing equipment
Experience supporting deviation investigations, root cause analysis, and CAPA implementation
Ability to read and interpret technical drawings, equipment manuals, and engineering specifications
Strong organizational skills and attention to detail in a fast-paced, compliance-driven environment

Job Duties

Supervise and coordinate daily activities of maintenance technicians and contractors, ensuring efficient task delegation and execution
Ensure all maintenance work complies with GMP, safety, and environmental regulations
Plan, schedule, and manage preventive and corrective maintenance schedules for GMP-critical equipment and systems to minimize downtime and ensure operational continuity
Maintain accurate and timely documentation of maintenance activities in the Computerized Maintenance Management System (CMMS)
Lead troubleshooting efforts and conduct root cause analysis for equipment failures, implementing corrective actions
Collaborate with Quality Assurance, Manufacturing, and Engineering teams to ensure equipment and facility readiness for production and audits
Participate in audits and inspections conducted by internal teams and regulatory agencies, providing necessary documentation and support