SR. RESEARCH ASSOCIATE/ASSOCIATE SCIENTIST, NONCLINICAL DEVELOPMENT
Job Overview
Employment Type
Full-time
Compensation
Salary
Range $108,000.00 - $150,000.00
Work Schedule
Standard Hours
Benefits
Competitive compensation package
Annual cash bonus
Long-term incentives
Employee Stock Purchase Plan (ESPP)
401(k) plan with ROTH and company match
Comprehensive health plans
Flexible health and commuter spending accounts
Life and Disability Insurance
paid time off including holidays and parental leave
Onsite gym
Onsite parking with electric vehicle charging stations
Free shuttle (Caltrain)
Company-subsidized lunches
fully stocked breakrooms
Job Description
Adicet Bio, Inc. is a pioneering clinical stage biotechnology company focused on discovering and developing innovative allogeneic gamma delta T cell therapies aimed at treating autoimmune diseases and various forms of cancer. As an industry leader, Adicet Bio specializes in advancing a portfolio of "off-the-shelf" gamma delta T cells that are engineered with chimeric antigen receptors (CARs) designed to provide durable, effective therapeutic activity in patients. Their cutting-edge work integrates advanced genetic engineering techniques with immunotherapy to develop revolutionary treatments that hold the promise of improving patient outcomes in areas with high unmet medical needs. For more information about their pioneering research and pipeline, interested candidates and stakeholders can visit the company website at www.adicetbio.com.
The position offered is for a Research Associate/Associate Scientist in the Nonclinical Development team at Adicet Bio. This full-time role is situated at their state-of-the-art facility where the company's cutting edge scientific research is conducted. The ideal candidate will play a crucial role in coordinating and executing in vivo and ex vivo nonclinical studies focused on evaluating Adicet's immune-cell and gene-therapy platforms. This involves a comprehensive array of activities including efficacy, pharmacokinetic/pharmacodynamic, and safety assessments primarily using murine oncology and immunology models.
As a Research Associate/Associate Scientist, you will contribute significantly to study design, experimental planning, timeline formulation, and data-driven decision-making processes that are essential for advancing the scientific programs within the company’s pipeline. This role requires collaboration with multiple cross-functional teams as well as external contract research organizations to successfully coordinate the execution of studies. The candidate will be responsible for troubleshooting technical challenges that arise during experiments and ensuring that the study endpoints align precisely with the overarching program goals. Tasks also include performing necropsies and processing tissues to support downstream analyses like flow cytometry, qPCR/ddPCR, and ELISA. These efforts are central to characterizing pharmacologic activity and elucidating the mechanisms of action of novel therapeutics.
Adicet fosters a collaborative, high-performing work environment by emphasizing in-person engagement with a requirement for employees to be onsite at least three days per week, specifically Tuesday through Thursday, to encourage team interaction and communication. The company offers a competitive compensation package featuring base salary, annual cash bonus, long-term equity incentives, an Employee Stock Purchase Plan (ESPP), and a 401(k) plan with ROTH options and a 4.5% company match. The employee wellness initiatives include comprehensive medical, dental and vision plans, flexible health and commuter spending accounts, life and disability insurance programs, and additional voluntary insurance offerings. Paid time off benefits are generous, encompassing 13 company holidays, a paid winter break, vacation, sick days, and paid parental leave.
The workplace is designed for comfort and convenience with features such as an onsite gym, other fitness options, onsite parking with EV charging stations, free shuttle service linking to Caltrain, subsidized daily onsite lunches, and fully stocked breakrooms. Adicet is deeply committed to diversity and equal opportunity, ensuring that all qualified applicants receive consideration without discrimination on any protected basis. Working at Adicet means being part of a forward-thinking, science-driven company dedicated to transforming patient lives through groundbreaking therapies while supporting a collaborative, innovative culture that values and nurtures its people.
The position offered is for a Research Associate/Associate Scientist in the Nonclinical Development team at Adicet Bio. This full-time role is situated at their state-of-the-art facility where the company's cutting edge scientific research is conducted. The ideal candidate will play a crucial role in coordinating and executing in vivo and ex vivo nonclinical studies focused on evaluating Adicet's immune-cell and gene-therapy platforms. This involves a comprehensive array of activities including efficacy, pharmacokinetic/pharmacodynamic, and safety assessments primarily using murine oncology and immunology models.
As a Research Associate/Associate Scientist, you will contribute significantly to study design, experimental planning, timeline formulation, and data-driven decision-making processes that are essential for advancing the scientific programs within the company’s pipeline. This role requires collaboration with multiple cross-functional teams as well as external contract research organizations to successfully coordinate the execution of studies. The candidate will be responsible for troubleshooting technical challenges that arise during experiments and ensuring that the study endpoints align precisely with the overarching program goals. Tasks also include performing necropsies and processing tissues to support downstream analyses like flow cytometry, qPCR/ddPCR, and ELISA. These efforts are central to characterizing pharmacologic activity and elucidating the mechanisms of action of novel therapeutics.
Adicet fosters a collaborative, high-performing work environment by emphasizing in-person engagement with a requirement for employees to be onsite at least three days per week, specifically Tuesday through Thursday, to encourage team interaction and communication. The company offers a competitive compensation package featuring base salary, annual cash bonus, long-term equity incentives, an Employee Stock Purchase Plan (ESPP), and a 401(k) plan with ROTH options and a 4.5% company match. The employee wellness initiatives include comprehensive medical, dental and vision plans, flexible health and commuter spending accounts, life and disability insurance programs, and additional voluntary insurance offerings. Paid time off benefits are generous, encompassing 13 company holidays, a paid winter break, vacation, sick days, and paid parental leave.
The workplace is designed for comfort and convenience with features such as an onsite gym, other fitness options, onsite parking with EV charging stations, free shuttle service linking to Caltrain, subsidized daily onsite lunches, and fully stocked breakrooms. Adicet is deeply committed to diversity and equal opportunity, ensuring that all qualified applicants receive consideration without discrimination on any protected basis. Working at Adicet means being part of a forward-thinking, science-driven company dedicated to transforming patient lives through groundbreaking therapies while supporting a collaborative, innovative culture that values and nurtures its people.
Job Requirements
- Bachelor's degree in biological sciences or related field
- 5+ years of relevant R&D experience or Master's degree with 3+ years of experience
- Experience in immuno-oncology preferably in industry
- Experience designing and conducting in vivo murine xenograft or humanized immunology models
- Proficiency in therapeutic agent administration via intravenous, intraperitoneal, and subcutaneous routes in mice
- Technical skills in blood collection, tissue necropsy, and sample processing for flow cytometry
- Experience in aseptic mammalian cell culture
- Hands-on experience with IVIS imaging platforms
- Excellent organizational and communication skills
- Ability to work independently and troubleshoot
- Ability to manage multiple priorities in a collaborative environment
Job Qualifications
- Bachelor's degree in biological sciences or related field with 5+ years of relevant R&D experience or Master's degree with 3+ years of experience preferably in immuno-oncology within industry
- Significant experience designing, executing, analyzing, and interpreting in vivo studies using murine xenograft disease models and/or humanized immunology models
- Proficiency administering therapeutic agents and establishing xenograft models through intravenous, intraperitoneal, and subcutaneous routes in mice
- Technical proficiency in blood collection including submandibular and tail-vein sampling, tissue necropsy, and sample processing for flow cytometry
- Experience with aseptic mammalian cell culture including maintenance and preparation of human cancer cell lines for nonclinical studies
- Hands-on experience with in vivo bioluminescence and/or fluorescence imaging using IVIS platforms
- Preferred experience with flow cytometry, ELISA, qPCR/ddPCR, and cytokine bead-based assays
- Excellent organizational, communication, data analysis, and technical documentation skills
- Ability to work independently and troubleshoot scientific and technical challenges
- Ability to manage multiple priorities and thrive in a fast-paced, collaborative research environment
Job Duties
- Coordinate and execute in vivo and ex vivo nonclinical studies to evaluate immune-cell and gene-therapy platforms
- Contribute to study design, experimental planning, timeline development, and data-driven decision-making
- Collaborate with cross-functional teams and external contract research organizations to coordinate study execution and troubleshoot challenges
- Perform necropsies and process tissues for downstream analyses including flow cytometry, qPCR/ddPCR, and ELISA
- Maintain accurate, complete, and well-organized experimental records in accordance with quality standards
Job Criteria
Experience
Mid Level (3-7 years)
Job Location
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