Applied BioCode, Inc.

Applied BioCode, Inc. is a biotechnology company specializing in the development and commercialization of multiplex diagnostic testing products for the in-vitro diagnostics (IVD) market. Founded in 2008 and headquartered in Santa Fe Springs, California, the company has established itself as a leader in high-throughput molecular diagnostics.

Central to Applied BioCode's innovation is its proprietary Barcoded Magnetic Bead (BMB) technology. This bio-inspired system integrates digital barcodes with immuno- and molecular chemistry, enabling the detection of up to 4,096 unique biomarkers or pathogens with exceptional accuracy. The BMBs are micro-sized beads, roughly the diameter of a human hair, tagged with specific probes that facilitate precise identification of biological targets.

The company's flagship product, the BioCode® MDx-3000, is an automated molecular diagnostic system designed for high-throughput multiplex testing. This system streamlines PCR amplification, hybridization, and detection, allowing laboratories to process up to 188 patient samples in an 8-hour shift. It supports simultaneous analysis of multiple syndromic panels, enhancing operational efficiency and reducing turnaround times.

Applied BioCode offers various diagnostic panels tailored to infectious diseases. The BioCode® Gastrointestinal Pathogen Panel (GPP) detects 17 pathogens associated with gastroenteritis, including viruses, bacteria, and parasites. Similarly, the BioCode® Respiratory Pathogen Panel (RPP) identifies 17 pathogens linked to upper respiratory infections.

In response to the COVID-19 pandemic, the company developed the BioCode® SARS-CoV-2 Assay and the BioCode® CoV-2 Flu Plus Assay, which simultaneously detect SARS-CoV-2 and influenza viruses, aiding in differentiation of respiratory infections.

Leadership

In 2023, Applied BioCode appointed Dr. Beth Laderman as Chief Scientific Officer. Dr. Laderman brings over 25 years of experience in medical diagnostics. Her leadership aims to expand the MDx-3000 platform and explore new applications for the BMB technology.

Patents and Certifications

The company has secured multiple patents, including one for its digital barcode technology, further solidifying its position in the multiplex diagnostic testing market.

Applied BioCode's products are CE-Marked for use in European countries and have received Emergency Use Authorization (EUA) from the U.S. FDA for certain assays. This reflects the company's commitment to global healthcare solutions.

Locations

Applied BioCode operates from the following locations:

• Santa Fe Springs, California (Headquarters)
• Downey, CA, USA