21c Museum Hotels

21c Museum Hotels is a unique hospitality brand that seamlessly integrates contemporary art museums, boutique hotels, and chef-driven restaurants to create an immersive cultural experience.

Founded in 2006 by art collectors and preservationists Laura Lee Brown and Steve Wilson, the brand's inaugural location in Louisville, Kentucky, revitalized historic 19th-century warehouses into a vibrant center for art, culture, and community engagement.

The brand's mission is to make contemporary art accessible to the public and to positively impact the communities it serves.

Each 21c Museum Hotel features a multi-venue contemporary art museum, a boutique hotel with thoughtfully designed guest rooms, and a restaurant that emphasizes local ingredients and culinary creativity.

This fusion of art, hospitality, and gastronomy offers guests a distinctive and enriching travel experience.

Locations

As of July 2025, 21c Museum Hotels operates in several cities across the United States, including:

• Bentonville, Arkansas
• Chicago, Illinois
• Cincinnati, Ohio
• Durham, North Carolina
• Lexington, Kentucky
• Louisville, Kentucky
• St. Louis, Missouri

Each location offers a curated selection of contemporary art exhibitions, site-specific installations, and cultural programming that reflect the local community's spirit and history.

The on-site restaurants, led by dedicated chefs, provide unique dining experiences that highlight regional flavors and support local farmers and producers.

Partnership and Growth

In 2018, 21c Museum Hotels expanded its global presence by joining the MGallery Hotel Collection, part of AccorHotels.

This partnership has facilitated the brand's growth and allowed it to offer its distinctive blend of art and hospitality to a broader audience.

Experience

Whether you're an art enthusiast, a culinary aficionado, or a traveler seeking a unique and enriching experience, 21c Museum Hotels provides a compelling destination that celebrates the intersection of art, culture, and hospitality.

Additional Locations

• Bentonville, AR, USA
• Lexington, KY, USA
• Cincinnati, OH, USA
• Durham, NC, USA
• Louisville, KY, USA